A Pharmacists Review of Medications for Hashimotos and Hypothyroidism Dr Izabella Wentz, PharmD
The conversion from T4 to T3 can be impeded by numerous factors, including nutrient deficiencies, stress, infections, and impaired liver and gut activity. Generally, the rule of thumb I like to consider is that if your TSH is elevated, and you have thyroid symptoms, you may benefit from starting thyroid medications. While our symptoms can provide a clue that something is off, our Testosterone cypionate labs can tell us if the reason we’re feeling unwell could be due to our medications.
While T4 is far more abundant, it is more of a storage molecule, whereas T3 is more active and potent at the cellular level. Indeed, T3 is what helps deliver oxygen and energy to your cells. Thyroid hormone production, secretion, and distribution throughout the body is a highly complex process.
- Although not all of these side effects may occur, if they do occur they may need medical attention.
- Closely monitor infants during the first 2 weeks of thyroid hormone therapy for cardiac overload, arrhythmias, and aspiration from avid suckling.
- The amount of medicine that you take depends on the strength of the medicine.
- Serum T4 levels can be used to test the effectiveness of all thyroid medications except products containing liothyronine sodium.
- Part of the reason many providers do not prescribe it is because they do not have specialized training in using other medications besides T4 for hypothyroid care.
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About 20 percent of our T3 hormone comes from thyroid secretion directly, while the remaining 80 percent is produced when Thyroxine (T4) is naturally converted to T3 within our bodies. While T4 is 300 percent less biologically active than T3, it is critical to our body’s ability to produce adequate and healthy levels of the needed T3. That said, thyroid hormone medications are very individualized! What works for your friend may not be your best option, leaving you with lingering symptoms such as fatigue, anxiety, brain fog, and excess weight. The right thyroid hormone medication can reduce thyroid antibodies and slow down the progressive thyroid destruction, as well as provide the energy needed to continue to work towards one’s health. Thyroid hormone medications can also reduce the size of thyroid goiters and nodules, as well as reduce the likelihood of thyroid cancer.
DOSAGE AND ADMINISTRATION
Additionally, some patients prefer natural desiccated thyroid (NDT) medications, which combine T4 and T3 derived from porcine (pig) thyroid glands. Since thyroid hormone affects heart rate and metabolism, the impact of treatment of thyroid hormone on the control of diseases such as atrial fibrillation, diabetes and high cholesterol levels always should be considered. Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines.
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Some practitioners may even have an extreme aversion to prescribing T3 or combination therapies, given their knowledge of the inappropriate abuse of T3 medications in the 80s. Back then it was often – and inappropriately (and dangerously!) – prescribed as a weight loss medication (sometimes along with amphetamines!) by weight loss clinics. People were admitted to emergency rooms with serious cardio symptoms, some even in a coma. Some practitioners may have witnessed this, or had at least heard of it, so they’ve perhaps shied away from learning more. You can read more about this as well as other reasons practitioners may find it challenging to prescribe anything beyond T4 medications. We know that even small differences in dose and absorption levels may lead to adverse reactions and even therapeutic failure.